FIGURE 4 from Humanized Patient-derived Xenograft Models of Disseminated Ovarian Cancer Recapitulate Key Aspects of the Tumor Immune Environment within the Peritoneal Cavity
Year: 2024
Type: other
Abstract: Detection of TAMs in huNBSGW PDX tumor sections. A, Serial sections of huNBSGW PDX tumor tissue were labeled with human-specific antibodies against a mitochondrial protein to label all human cells and the TAM marker CD68. Scale bar, 100 μm. B, Quantification of the number of TAMs using HALO software to identify CD68+ cells. Values are no. of positive cells/100,000 cells. The box plots indicate the mean, minimum, and maximum. Black dots indicate values for each tumor analyzed (n = 2–3).
Language: English
Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4396660513