Factitious disorder presenting as sickle cell disease: a case report
Year: 2024
Type: article
Study design: Case Report
Abstract: Sickle cell disease (SCD) affects more than 7 million individuals worldwide.1 Almost a quarter of individuals with SCD will suffer a stroke by the age of 45,2 with a recurrence rate approaching 60% in the absence of therapy.3 Rapid intervention is often necessary for stroke and other complications of SCD, typically before the results of hemoglobinopathy evaluation become available.4 Unfortunately, this acuity of need may be exploited. Specifically, individuals may present with “factitious SCD”, whereby individuals purport to have SCD and present with symptoms and signs suggestive of severe SCD complications necessitating urgent treatment/intervention, yet fail to show any objective evidence of the disease upon subsequent laboratory investigation.
Authors: Jeremy W. Jacobs, Juliana Guarente, Julie K. Karp, Brenda J. Grossman, Alyssa F. Ziman, Andrea M. McGonigle, Thomas C. Binns, Tappy J. Gish, James D. Gorham, Yara A. Park, Ingrid Perez-Alvarez, James D. Burner, Zhen W. Mei, Dawn C. Ward, Jennifer S. Woo, Garrett S. Booth, Brian D. Adkins, Christopher B. Webb, Chisa Yamada, Grace M. Lee, Elizabeth Abels, Marisa B. Marques, Elizabeth S. Allen, Ross M. Fasano, Elizabeth P. Crowe, Aaron A.R. Tobian, Christopher A. Tormey, Evan M. Bloch
Institutions: Mayo Clinic, Thomas Jefferson University Hospital, Washington University in St. Louis, University of California, Los Angeles, Yale University, University of Virginia, University of North Carolina at Chapel Hill, University of North Carolina Health Care, Cedars-Sinai Medical Center, The University of Texas Southwestern Medical Center, City Of Hope National Medical Center, Vanderbilt University Medical Center, University of Michigan, Duke Medical Center, Baylor College of Medicine, University of Alabama at Birmingham, University of California San Diego, Emory University, Children's Healthcare of Atlanta, Johns Hopkins University, Johns Hopkins Medicine
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,000
OpenAlex ID: W4396686727