The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe
Year: 2024
Type: article
Study design: Observational Study
Abstract: BACKGROUND: We examined whether cannabis use contributes to the increased risk of psychotic disorder for non-western minorities in Europe. METHODS: We used data from the EU-GEI study (collected at sites in Spain, Italy, France, the United Kingdom, and the Netherlands) on 825 first-episode patients and 1026 controls. We estimated the odds ratio (OR) of psychotic disorder for several groups of migrants compared with the local reference population, without and with adjustment for measures of cannabis use. RESULTS: The OR of psychotic disorder for non-western minorities, adjusted for age, sex, and recruitment area, was 1.80 (95% CI 1.39-2.33). Further adjustment of this OR for frequency of cannabis use had a minimal effect: OR = 1.81 (95% CI 1.38-2.37). The same applied to adjustment for frequency of use of high-potency cannabis. Likewise, adjustments of ORs for most sub-groups of non-western countries had a minimal effect. There were two exceptions. For the Black Caribbean group in London, after adjustment for frequency of use of high-potency cannabis the OR decreased from 2.45 (95% CI 1.25-4.79) to 1.61 (95% CI 0.74-3.51). Similarly, the OR for Surinamese and Dutch Antillean individuals in Amsterdam decreased after adjustment for daily use: from 2.57 (95% CI 1.07-6.15) to 1.67 (95% CI 0.62-4.53). CONCLUSIONS: The contribution of cannabis use to the excess risk of psychotic disorder for non-western minorities was small. However, some evidence of an effect was found for people of Black Caribbean heritage in London and for those of Surinamese and Dutch Antillean heritage in Amsterdam.
Source: Psychological Medicine
Authors: J. P. Selten, M. Di Forti, D. Quattrone, P. B. Jones, H. E. Jongsma, C. Gayer-Anderson, A. Szöke, P. M. Llorca, C. Arango, M. Bernardo, J. Sanjuan, J. L. Santos, M. Arrojo, I. Tarricone, D. Berardi, A. Lasalvia, S. Tosato, C. la Cascia, E. Velthorst, E. M. A. van der Ven, L. de Haan, B. P. Rutten, J. van Os, J. B. Kirkbride, C. M. Morgan, R. M. Murray, F. Termorshuizen
Institutions: Maastricht University Medical Centre, GGZ Rivierduinen, King's College London, National Health Service, University of Cambridge, Cambridgeshire and Peterborough NHS Foundation Trust, University Medical Center Groningen, University of Groningen, Inserm, Université Paris-Est Créteil, Fondation FondaMental, Assistance Publique – Hôpitaux de Paris, Institut Mondor de Recherche Biomédicale, Université Clermont Auvergne, Hospital General Universitario Gregorio Marañón, Centro de Investigación Biomédica en Red de Salud Mental, Hospital Clínic de Barcelona, Consorci Institut D'Investigacions Biomediques August Pi I Sunyer, Universitat de Barcelona, Universitat de València, Hospital Virgen de la Luz, Complejo Hospitalario Universitario de Santiago, Instituto de Investigación Sanitaria de Santiago, University of Bologna, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, University of Palermo, GGZ Noord-Holland-Noord, Vrije Universiteit Amsterdam, Amsterdam UMC Location University of Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Utrecht University, University Medical Center Utrecht, University College London
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,450
Funders: Fundación Alicia Koplowitz, Amsterdam University Medical Centers, King's College London, Universiteit van Amsterdam, Universiteit Utrecht, Vrije Universiteit Amsterdam, Università degli Studi di Palermo, Università degli Studi di Verona, National Institutes of Health, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, Economic and Social Research Council
OpenAlex ID: W4396778739