Work

Enhancing Ligand Pharmacokinetics While Retaining Dopamine D4 Receptor Potency and Selectivity via Bioisosteric Substitution of Amide Linkers with 1,2,3-Triazoles

Year: 2024

Type: article

Source: Journal of Pharmacology and Experimental Therapeutics

DOI: 10.1124/jpet.288.101080

Authors: Mohammad Alkhatib, Ashley N. Nilson, Franziska M. Jakobs, John N. Hanson, Joseph Ricchezza, Shannon Jordan, Norman Nguyen, Nitish Kasarla, Bryant Wang, Sergio Sola Garcia, Rana Rais, Barbara Slusher, R. Benjamin Free, David R. Sibley, Comfort A. Boateng, Thomas M. Keck

Institutions: Rowan University, National Institute of Neurological Disorders and Stroke, High Point University, Johns Hopkins University

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4396850021

FWCI:

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Related to: 10