Work

A step-by-step guide to fragmenting bundled actin filaments

Year: 2024

Type: article

Abstract: There has long been conflicting evidence as to how bundled actin filaments, found in cellular structures such as filopodia, are disassembled. In this issue, Chikireddy et al. (https://doi.org/10.1083/jcb.202312106) provide a detailed in vitro analysis of the steps involved in fragmentation of fascin-bundled actin filaments and propose a novel mechanism for severing two-filament bundles.

Source: The Journal of Cell Biology

DOI: 10.1083/jcb.202403191

Authors: Rachel S. Kadzik, David R. Kovar

Institution: University of Chicago

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W4396922237

FWCI:

Cites: 12

Cited by:

Related to: 10