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Supplementary Figure S2 from Developing Novel Genomic Risk Stratification Models in Soft Tissue and Uterine Leiomyosarcoma

Year: 2024

Type: supplementary-materials

Abstract: Supplementary Figure S2. MSKCC STLMS cohort. Genomic variables (gene level point mutations and copy number changes and chromosomal arm level changes) are input into the OncoCast model using the elastic net (“ENET”) approach, with outcome being overall survival. Variable importance is assigned and visualized in a plot by selection frequency (the event frequency of that feature in the data) and Cox proportional hazard ratios. Dotted lines indicate threshold of 0.55 selection frequency and hazard ratio of 1.

DOI: 10.1158/1078-0432.25826466.v1

Authors: Josephine K. Dermawan, Sarah Chiang, Samuel Singer, Bhumika Jadeja, Martee L. Hensley, William D. Tap, Sujana Movva, Robert G. Maki, Cristina R. Antonescu

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4396937419

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