Work

Dynamic measurement of airway surface liquid volume with an ex vivo trachea-chip

Year: 2024

Type: article

Abstract: An “ ex vivo trachea chip” integrates a tissue explant with a micromachined device, enables dynamic measurements of airway surface liquid volume, and reveals physiology of airway surface liquid secretion and absorption.

Source: Lab on a Chip

DOI: 10.1039/d4lc00134f

Authors: Michael Scott, Lei Lei, Kaleb C. Bierstedt, Paul B. McCray, Yuliang Xie

Institutions: University of Iowa, University of Iowa Stead Family Children’s Hospital

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Cystic Fibrosis Foundation, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Biomedical Imaging and Bioengineering

Awards: Developing Trachea-on-a-chip to Study Particle Mucociliary Transport in Airways, Molecular Therapies for Cystic Fibrosis Lung Disease, G7291381728, Precision Medicine Center for Cystic Fibrosis, An Engineered Surface of Mucociliary Transport for Medical Devices

OpenAlex ID: W4398239734

FWCI: 0.109

Cites: 66

Cited by: 1

Related to: 10