Work

The Path to Progress: Glucagon-like Peptide 1 Agonists, Individualized Care, and Overcoming Goal-Directed Medical Therapy Barriers in Diabetes and CKD

Year: 2024

Type: editorial

Abstract: The origin of glucagon-like peptide 1 agonists (GLP-1RA) can be traced back to a shy, unassuming, slow-moving reptile found within the southwestern regions of the United States. In 1990, an endocrinologist named Dr. John Eng from the Veterans Administration Center in Bronx, NY, isolated exendin-4 from the venomous saliva of the famed Gila monster. Exendin-4 is an incretin hormone that stimulates insulin production during periods of high glucose loads in the Gila monster, known to consume only 3-4 meals per year.

Source: Kidney International Reports

DOI: 10.1016/j.ekir.2024.05.027

Authors: Sophia L. Ambruso, Matthew R. Weir

Institutions: VA Eastern Colorado Health Care System, University of Colorado Anschutz, University of Colorado Denver, University of Maryland, Baltimore

Language: English

Topic: Diabetes Treatment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,800

OpenAlex ID: W4399040091

Cites: 7

Cited by:

Related to: 10