Work

Sex-based differences in persistent lung inflammation following influenza infection of juvenile outbred mice

Year: 2024

Type: article

Abstract: This study identifies sex-based differences in persistent lung inflammation following influenza infection in an outbred, juvenile animal model of pediatric infection. These findings indicate the importance of considering sex and age as variable in infectious disease research.

Source: American Journal of Physiology-Lung Cellular and Molecular Physiology

DOI: 10.1152/ajplung.00407.2023

Authors: Brydie R. Huckestein, Danielle Antos, Michelle L. Manni, Kelly Zeng, Leigh M. Miller, Kristen L. Parenteau, Stacy L. Gelhaus, Steven J. Mullett, Jason E. Shoemaker, John F. Alcorn

Institutions: University of Pittsburgh, Children's Hospital of Pittsburgh

Language: English

Topic: Influenza Virus Research Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, NIH Office of the Director, National Institute of Allergy and Infectious Diseases

Awards: G100797987, G1263119799, Targeting metabolism to improve outcomes following severe influenza infection, Bringing Untargeted Metabolomics to Pitt, Mathematical Modeling of Influenza Severity in Outbred Mice, An Exploris 240 for Metabolomics

OpenAlex ID: W4399117124

FWCI: 1.213

Cites: 58

Cited by: 4

Related to: 10