Supplementary Figure S2 from Best Overall Response–Associated Signature to Doxorubicin in Soft Tissue Sarcomas: A Transcriptomic Analysis from ANNOUNCE
Year: 2024
Type: supplementary-materials
Abstract: Expression biomarker ESR1. (A) Boxplot shows the significant subtype difference of ESR1 expression in uterine leiomyosarcoma tumors (P = 0.00014). (B, C) Kaplan-Meier plots show patients with uterine leiomyosarcoma in CC3 had longer (B) PFS (6.97 months vs. 3.02 months) and (C) OS (21.47 months vs. 10.51 months) than those with uterine leiomyosarcoma not in CC3, although both P values were not significant. (D, E) The survival of patients with uterine leiomyosarcoma was significantly associated with ESR1 mRNA expression status. “High” or “low” ESR1 status was dichotomized by zero after the ESR1 expression values were Z scored. Abbreviation: NA, not available.
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4399299013