Work

FIGURE 2 from Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer

Year: 2024

Type: other

Abstract: Frequently occurring molecular coalterations in CCNE1-amplified EGC. Frequency of comutated genes among all CCNE1-amplified and nonamplified EG adenocarcinoma by WES and NGS (A). CNAs co-occurring with CCNE1 amplification (B). LOH with CCNE1 amplification (C). HER2 overexpression or ERBB2 amplification in CCNE1-amplified EG adenocarcinoma by CISH assays, IHC, or NGS (D). Statistical significance is displayed as the following: *, q < 0.05; **, q < 0.01; ***, q < 0.001; ****, q < 0.0001.

DOI: 10.1158/2767-9764.25958967.v1

Authors: Naryan Rustgi, Sharon Wu, Timothy Samec, Phillip Walker, Joanne Xiu, Emil Lou, Sanjay Goel, Anwaar Saeed, Ryan H. Moy

Language: English

Topic: Gastric Cancer Management and Outcomes

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4399302315

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