Work

Supplemental Figure S5 from Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Year: 2024

Type: supplementary-materials

Abstract: This figure shows purification of the recombinant human thymidylate synthase (TS) and in vitro inhibition by pyrrolo[3,2-d]pyrimidine antifolates.

DOI: 10.1158/1535-7163.25964884

Authors: Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S. Dekhne, Xun Bao, Md. Junayed Nayeen, Mathew Schneider, Jade M. Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B. Back, Charles E. Dann, Aleem Gangjee, Zhanjun Hou, Larry H. Matherly

Language: English

Topic: Folate and B Vitamins Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4399343029

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