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Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin

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Year: 2024
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.4c05090
Authors: Bibek Dhakal, Appi Mandhapati, Pradheep Eradi, Simon Park, Kirby Fibben, Kaicheng Li, Ashley DeYong, Samira Escopy, Geeta Karki, Diane D. Park, Carolyn A. Haller, Erbin Dai, Lijun Sun, Wilbur A. Lam, Elliot L. Chaikof
Institutions: Beth Israel Deaconess Medical Center, Harvard University, Emory University, Wyss Institute for Biologically Inspired Engineering, Massachusetts Institute of Technology
Language: English

Topic: Carbohydrate Chemistry and Synthesis
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Harvard Medical School, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Facile Synthesis of Glycosulfopeptides and Related Bioconjugates, A PSGL-1 Glycopeptide Mimetic for Treatment of Metabolic Syndrome, G6397800322, A PSGL-1 Glycopeptide Mimetic for Treatment of Venous Thromboembolism
OpenAlex ID: W4399567795
FWCI: 2.467
Cites: 76
Cited by: 17
Related to: 10
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