Work

mashr: Multivariate Adaptive Shrinkage

Year: 2020
Type: dataset
Abstract: Implements the multivariate adaptive shrinkage (mash) method of Urbut et al (2019) <doi:10.1038/s41588-018-0268-8> for estimating and testing large numbers of effects in many conditions (or many outcomes). Mash takes an empirical Bayes approach to testing and effect estimation; it estimates patterns of similarity among conditions, then exploits these patterns to improve accuracy of the effect estimates. The core linear algebra is implemented in C++ for fast model fitting and posterior computation.
Language: English
Open Access status: gold
OpenAlex ID: W4399569879
Cites: 1
Cited by: 1
Related to: 10