FIGURE 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Year: 2024
Type: other
Abstract: Microbial composition variance in relation to chemotherapy response in patients with bladder cancer. A, Proportional representation of the GM's phylogenetic composition in patients showing CR versus NR to NAC (Also depicted in C). B, Alpha diversity metrics compared across response groups, highlighting minimal statistical disparities. D, Weighted UniFrac PCoA depicting the lack of distinct microbial clustering by response category. E–G, Venn diagram and LEfSe analysis illustrating unique and differentially abundant microbial taxa associated with NAC responses, enriched in either CR or NR groups, along with a taxonomic cladogram delineating these associations.
Authors: Laura Bukavina, Rashida Ginwala, Mohamed Eltoukhi, Mohit Sindhani, Megan Prunty, Daniel M. Geynisman, Pooja Ghatalia, Henkel Valentine, Adam Calaway, Andres F. Correa, Jason R. Brown, Kirtishri Mishra, Elizabeth R. Plimack, Alexander Kutikov, Mahmoud Ghannoum, Mohammed Elshaer, Mauricio Retuerto, Lee Ponsky, Robert G. Uzzo, Philip H. Abbosh
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4399736378