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Figure S18 from HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity

Year: 2024

Type: other

Abstract: Fig. S18. Correlation of the effect of HDAC6 inhibitors on proteasome activity with the effect on MHC-I antigen presentation. a.) Effect of tubastatin-A on proteasome activity correlated with the effect on pan HLA-ABC antigen presentation. b.) Effect of ACY-738 on proteasome activity correlation with the effect on pan HLA-ABC antigen presentation c.) Effect of ACY-1215 on proteasome activity correlated with the effect on pan HLA-ABC antigen presentation.

DOI: 10.1158/2767-9764.26058209.v1

Authors: Priyanka S. Rana, James J. Ignatz-Hoover, Byung-Gyu Kim, Ehsan Malek, Yuriy Federov, Drew Adams, Timothy Chan, James J. Driscoll

Language: English

Topic: Histone Deacetylase Inhibitors Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4399772395

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