Work

Radiosynthesis and Quality Control of [18F] PSMA-1007 at the Cyclotron Facility of National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for Diagnosis of Prostate Cancer

Year: 2024

Type: article

Abstract: Radiolabeled tracers targeting prostate-specific membrane antigen (PSMA) have revolutionized PET imaging for prostate cancer diagnosis. Here, we present the inaugural production and quality control assessment of (18F) PSMA-1007 at the National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Bangladesh. The synthesis, conducted via a one-step procedure, yielded remarkable radiochemical yields (46.85%) with synthesis time 40 minutes. Quality control measures adhered to European Pharmacopoeia standards, enabling clinical deployment across Nuclear Medicine and PET-CT centers in Bangladesh. This pioneering effort marks a significant advancement in prostate cancer imaging within the region. Bangladesh J. Nuclear Med. 26(2): 198-200, 2023

Source: Bangladesh Journal of Nuclear Medicine

DOI: 10.3329/bjnm.v26i2.71484

Authors: Md Jashim Uddin, Mohammad Anwar Ul Azim, Sanchoy Chandra Biswasarma, Md Saiful Islam, Sanjida Islam, Mustafa Mamun, Ferdoushi Begum, Md Nahid Hossain, Md Shohag Mia, Hasan Mehdi, Md Nur E Alam Siddiquee, Muhtasin Kadir

Institutions: Bangladesh Medical University, National Institute of Nuclear Medicine & Allied Sciences, Bangladesh Atomic Energy Commission

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4399924397

FWCI:

Cites: 8

Cited by:

Related to: 10