Failed Induction of the TH1 System in TH2 Dominant Patients: The Cancer-Permissive Immune Macroenvironment.
Year: 2024
Type: article
Abstract: T cell activation, yielding a cancer-permissive tumor microenvironment and a poorer prognosis in patients with existing cancers. This paper proposes a conceptual framework that connects established elements in the existing research and points to the utility of a patient profiling process, aimed at personalization of treatment through identification and targeting of elements in each patient's tumor microenvironment and macroenvironment that contribute to unfavorable prognosis.
Source: PubMed Central
Author: Samuel F Yanuck
Institution: University of North Carolina at Chapel Hill
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4399985830