Work

Whole genome analysis of spontaneous antimicrobial resistance in Liberibacter crescens suggests long-term efficacy for antimicrobial treatment of citrus greening disease

Year: 2024

Type: article

Abstract: Currently, oxytetracycline and streptomycin are being applied to citrus groves in Florida for the control of citrus greening disease caused by the unculturable bacterium Candidatus Liberibacter asiaticus. Here, the closest cultured relative, L. crescens , was used to estimate the frequency of spontaneous antimicrobial resistance of Liberibacter spp. Results yielded thirteen streptomycin and zero oxytetracycline mutants after exposing 13 billion cells to the antimicrobials. These low rates, alongside the restrictive habitats of the vector and pathogen, suggest resistance may develop very slowly, if at all. Thus, the treatments will likely remain useful long enough before pathogen-resistant or -tolerant genotypes are deployed.

Source: Journal of Citrus Pathology

DOI: 10.5070/c411262263

Authors: Paula Rios Glusberger, Jordan T. Russell, Alexa R. Cohn, Joseph R. Petrone, Kin-Kwan Lai, Eric W. Triplett

Institutions: University of California, Riverside, University of Florida, Institute of Food and Agricultural Sciences

Language: English

Topic: Phytoplasmas and Hemiptera pathogens

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Citrus Research and Development Foundation