Work

An Investigation of Honey’s Effects on Small Intestine Microbial Composition and Virulence Expression of the Foodborne Pathogen Enterotoxigenic E. coli

Year: 2024

Type: article

Abstract: Objectives: Previously, our lab has shown that the foodborne pathogen enterotoxigenic E. coli (ETEC) displayed a significant decrease in survival in an in vitro gastric digestion with honey, as compared to a simple sugar control. However, this effect did not persist or prove to be protective in an in vitro small intestine fermentation in the presence of a mock community of small intestine microbial organisms (SIMO). Here, we build on this existing work to examine changes in microbial community composition, as well as abundance of the virulence factor sta2, in response to an in vitro small intestine fermentation with gastric-digested honey.

Source: Current Developments in Nutrition

DOI: 10.1016/j.cdnut.2024.103492

Authors: Ste Traxler, David Storms, Alyce R Faso, Danielle G Lemay, Mary E Kable

Institutions: University of California, Davis, Western Human Nutrition Research Center

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,000