Predictors of Rotavirus and Viral Diarrhea Etiology in Young Children: A Secondary Cross-Sectional Analysis of the ABCD Trial
Year: 2024
Type: article
Abstract: food groups consumed in the past 24 hours.The difference in CDDS between endline and baseline (CDDS diff ) in control (no intervention), I1 (EDU + MF), and I2 (EDU + MF + CS) was assessed using multivariate regression with cluster robust standard errors, adjusted for baseline characteristics differing between all study arms.Potential modification effect by marriage structure, maternal age, maternal education, child age, and child sex, were assessed, considering multiple comparison with Bonferroni correction.Results: At baseline, mean CDDS was 3.2 Æ 1.2 in control, 2.8 Æ 1.1 in I1, and 2.7 Æ 1.1 in I2.We observed significant increase in CDDS from baseline to endline in control (CDDS diff : 0.49, 95% CI: 0.22, 0.75), I1 (CDDS diff : 0.55, 95% CI: 0.37, 0.74), and I2 (CDDS diff : 0.75, 95% CI: 0.53, 0.96).However, no significant differences were observed in CDDS diff between any of the three study arms.The null effect was consistently observed by the potential modifiers examined.Conclusions: Short-term nutrition education and microfinance with or without couples' strengthening did not improve CDDS.The overall poor agricultural yields and inflated food prices in 2021-2022 and the residual confounding due to unmeasured differences between the control and intervention groups may have contributed to lack of intervention impact in our analysis.Our findings highlight the need to further investigate the mechanisms that drive changes in child diets in highly food-insecure and resource-scarce settings in rural Niger.
Authors: Sarah Somji, Christopher Sudfeld, Christopher Duggan, Karim Manji, Tahmeed Ahmed, Md Jobayer Chisti, Usha Dhingra, Sunil Sazawal, Benson Singa, Judd Walson, Patricia Pavlinac, Naor Bar-Zeev, Eric Houpt, Queen Dube, Karen Kotloff, Samba Sow, Mohammad Tahir Yousafzai, Farah Qamar, Rajiv Bahl, Ayesha De Costa, Jonathon Simon, Per Ashorn
Institutions: Tampere University, Harvard University, Boston Children's Hospital, Muhimbili University of Health and Allied Sciences, International Centre for Diarrhoeal Disease Research, Kenya Medical Research Institute, Johns Hopkins University, University of Washington, University of Liverpool, University of Virginia, Queen Elizabeth Central Hospital, University of Maryland, College Park, Aga Khan University, World Health Organization
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $5,000
OpenAlex ID: W4400149374