Supplementary Figures S1-S4 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis
Year: 2024
Type: supplementary-materials
Abstract: Figure S1. Landscape of somatic mutations and cytogenetics in Moffitt MF cohort. Figure S2. Effects of enforced MYC expression in HSCs in vivo. Figure S3. MYC-induced changes in hematopoietic sub-populations and colony forming potential. Figure S4. The JAK/STAT, PI3K/AKT, MEK/ERK, and alarmin pathways in MYC-driven MF.
Authors: Nicole D. Vincelette, Xiaoqing Yu, Andrew T. Kuykendall, Jungwon Moon, Siyuan Su, Chia-Ho Cheng, Rinzine Sammut, Tiffany N. Razabdouski, Hai V. Nguyen, Erika A. Eksioglu, Onyee Chan, Najla Al Ali, Parth C. Patel, Dae H. Lee, Shima Nakanishi, Renan B. Ferreira, Elizabeth Hyjek, Qianxing Mo, Suzanne Cory, Harshani R. Lawrence, Ling Zhang, Daniel J. Murphy, Rami S. Komrokji, Daesung Lee, Scott H. Kaufmann, John L. Cleveland, Seongseok Yun
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4400214683