Supplementary Figures S5-S9 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis
Year: 2024
Type: supplementary-materials
Abstract: Figure S5. Changes in signaling in BM of trisomy 8+ TN-MF patient and MYC MF mice. Figure S6. Effects of silencing S100a9 in MYC-driven MF or overexpression of S100a9. Figure S7. Effects of inhibition of S100a9 or MYC in MYC-driven MF. Figure S8. Synthesis and Characterization of Tasquinimod. Figure S9. Synthesis and Characterization of MYCi975.
Authors: Nicole D. Vincelette, Xiaoqing Yu, Andrew T. Kuykendall, Jungwon Moon, Siyuan Su, Chia-Ho Cheng, Rinzine Sammut, Tiffany N. Razabdouski, Hai V. Nguyen, Erika A. Eksioglu, Onyee Chan, Najla Al Ali, Parth C. Patel, Dae H. Lee, Shima Nakanishi, Renan B. Ferreira, Elizabeth Hyjek, Qianxing Mo, Suzanne Cory, Harshani R. Lawrence, Ling Zhang, Daniel J. Murphy, Rami S. Komrokji, Daesung Lee, Scott H. Kaufmann, John L. Cleveland, Seongseok Yun
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4400214781