Work

Supplementary Figure S6 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs

Year: 2024

Type: supplementary-materials

Abstract: This figure shows representative images in the treatment of TPT (topotecan) and M1774 in small cell lung cancer organoids, and profiling of cell viability and DNA-damage molecules after drug treatment.

DOI: 10.1158/1535-7163.26190699.v1

Authors: Ukhyun Jo, Yasuhiro Arakawa, Astrid Zimmermann, Daiki Taniyama, Makito Mizunuma, Lisa M. Jenkins, Tapan K. Maity, Suresh Kumar, Frank T. Zenke, Naoko Takebe, Yves Pommier

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4400357550

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