Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency
Year: 2024
Type: article
Source: Nature Biotechnology
Institution: Boston University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: National Science Foundation, U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources, Division of Molecular and Cellular Biosciences
Awards: G279212540, G3399697213, G4454710804, G4703624085, G4998774151, G513387119, G6870337603, Characterization of a human-specific positive regulator of flavivirus infection, Research Training in Immunology, High Sensitivity In Vivo Imaging System with Integrated Micro-Computed Tomography for Animal Phenotyping Core, Multiplexed and Logical Control of the Mammalian Transcriptome Using Cas13, G7541296707, G8088829554, Graduate Research Fellowship Program (GRFP), In Vivo Imaging Analysis System - Xenogen IVIS Spectrum, Precise targeting of T1D specific T cells using CAR and peptide-MHC chimeric antigen ligands, Synthetic circuit technologies for precision control and signal processing in mammalian cells, Translational Research in Biomaterials, Precise tumor targeting with logic CAR circuits
OpenAlex ID: W4400422913