Year: 2026
Type: book-chapter
Abstract: Clinical interventions often target multiple components of a patient’s health and behavior. For example, this work is motivated by our involvement in a sequential multiple assignment randomized trial (SMART Lavori and Dawson, 2004 ; Murphy, 2005 ) on human immunodeficiency virus (HIV)/sexually transmitted infection (STI) prevention through electronic health (eHealth) interventions in adolescent men who have sex with men ( Mustanski et al., 2020 ). In this study, there are three primary outcomes of interest which are targeted by the interventions under study: (i) risky behavior, e.g., condomless anal sex; (ii) regular HIV/STI testing; and (iii) self-efficacy for condom use. These outcomes are ordered by importance, i.e., they are prioritized ( Finkelstein and Schoenfeld, 1999 ; Buyse, 2010 ), but it is not clear how one should define an optimal intervention strategy that reflects these priorities.
Source: Chapman & Hall/CRC eBooks
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4400480614