Work

Directly Suppressing MYC Function with Novel Alkynyl-Substituted Phenylpyrazole Derivatives that Induce Protein Degradation and Perturb MYC/MAX Interaction

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c00272

Authors: Can Zhao, Fang Zhao, Liuqing Yang, Yang Wang, Henian Wang, Fang Fang, Haojie Zuo, Zhi Li, Ge He, Wenhu Zhan, Xiaodong Ma

Institution: Anhui University of Traditional Chinese Medicine

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Anhui Province, Provincial Foundation for Excellent Young Talents of Colleges and Universities of Anhui Province, University Natural Science Research Project of Anhui Province

Awards: G1020698297, G4907002397, G5152037827, G5531437262, G6653407038

OpenAlex ID: W4400549647

FWCI: 1.811

Cites: 38

Cited by: 14

Related to: 10