Work

Electrophile Determines Cellular Phenotypes among XPO1-Targeting Small Molecules

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c00754

Authors: Yi Fan Chen, Yanqiu Shen, David F. Yan, Maryam Ghazala, Marc A. Scemama de Gialluly, Ramya Srinivasan, Amanda N. Farrar, Ryan M. Friedrich, Drew J. Adams

Institution: Case Western Reserve University

Language: English

Topic: Nuclear Structure and Function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Case Western Reserve University, Dr. Ralph and Marian Falk Medical Research Trust, National Institutes of Health, Harrington Discovery Institute, University Hospitals, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Medical Scientist Training Program, G6927102407, Functional Genomics Training Program (FGTP), Case Comprehensive Cancer Center Support Grant, Selective Inhibitors of T Cell Activation Target Exportin-1 at Cys528 to Suppress Pathological T Cell Activation

OpenAlex ID: W4400659670

FWCI: 1.294

Cites: 30

Cited by: 10

Related to: 10