The Development and Validation of the Comprehensive Assessment Tool for Challenges in Hemophilia (CATCH) 2.0
Year: 2024
Type: preprint
Abstract: Background The Comprehensive Assessment Tool of Challenges in Hemophilia (CATCH) was initially developed in 2018 and includes three versions: pediatric, adult, and caregiver. The original versions are lengthy, and scoring can be complex and time-consuming. Therefore, we developed and validated abbreviated versions of the CATCH (referred to as 2.0) and present data supporting their factor structure, reliability, and validity. Methods The analysis pooled data from three studies (N = 126 children, 232 adults, and 118 caregivers) and included individuals with hemophilia A and B. Clinical experts provided feedback regarding potential individual items for deletion, and exploratory factor analysis (EFA) was performed after selected items were removed. Confirmatory factor analysis (CFA) was used to evaluate measurement invariance of the CATCH 2.0. Reliability and validity were assessed using criterion measures; responsiveness was evaluated using the standard effect size and standardized response mean. We endeavored to estimate clinically meaningful change for each scale of the CATCH 2.0. Results The adult version of the CATCH 2.0 demonstrated good validity and reliability, with an excellent factor structure and evidence that it is appropriate for use with both hemophilia type A and type B. While the factor structure of the Pediatric and Caregiver versions was excellent, some measurement properties could not be established (e.g., test-retest reliability, known-groups validity, responsiveness), in part due to small sample sizes. Additionally, it was not possible to estimate anchor-based clinically meaningful changes for the three versions due to a lack of appropriate anchors. Conclusions The CATCH 2.0 is a more accessible self-report version of CATCH 1.0 and has adequate psychometric properties for most scales and versions. The reliability and validity demonstrated by these results, along with its brevity, should permit its use in both clinical research and practice.
Source: Research Square
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4400724387