Introducing CRAFT: The Center for Research and Advancement in Fragments and molecular Targets
Year: 2024
Type: editorial
Abstract: We introduce the Center for Research and Advancement in Fragments and Molecular Targets (CRAFT), a pioneering research center established in 2021 through a collaboration between the University of São Paulo (USP) and the Federal University of Goiás (UFG). CRAFT integrates fragment-based drug discovery (FBDD), artificial intelligence (AI), and structural biology to develop novel therapeutic strategies. We have created fragment and target libraries and utilize AI models to streamline the drug discovery process. We invite the global scientific community to collaborate with us in addressing neglected diseases, with the goal of enhancing research capabilities and fostering scientific innovation across Latin America.
Source: ACS Medicinal Chemistry Letters
Institutions: Universidade de São Paulo, Universidade Federal de Goiás
Language: English
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação de Amparo à Pesquisa do Estado de Goiás, Universidade de São Paulo, Universidade Federal de Goiás, National Institutes of Health, National Institute of Allergy and Infectious Diseases
Awards: G1036976577, G3690646728, G4207757979, Drug repurposing and search of selective inhibitors for human dihydroorotate dehydrogenase as a strategy in fighting against COVID-19, G510972860, G5332385560, G5514976981, G8724532333, Validation of Trypanosoma cruzi dihydroorotate dehydrogenase as a drug target for Chagas´disease.
OpenAlex ID: W4400905584