Work

Neonatal cardiopulmonary resuscitation: is ROSC enough?

Year: 2024

Type: article

Abstract: The study by Morin et al. examines a critical question with a profound short and long-term outcome after neonatal code events—what is the most effective way to provide cardiopulmonary resuscitation in this population at risk for short and long-term morbidity and mortality? They studied twenty infantile piglets and randomized to continuous chest compressions superimposed with sustained inflation (CC + SI) versus chest compressions with asynchronized ventilation (CCaV), hypothesizing the addition of SI would reduce time to return of spontaneous circulation (ROSC) following asphyxia-induced bradycardic arrest. CC + SI increased intrathoracic pressure, minute ventilation, and reduced duration of resuscitation compared CCaV in this model. The use of a gyrencephalic model of brain development is a strength of this study; however, numbers are small, and the study does not address long-term outcomes or brain injury post-arrest.

Source: Pediatric Research

DOI: 10.1038/s41390-024-03398-8

Authors: Robert M. Dietz, Fernando F. Gonzalez

Institutions: Children's Hospital Colorado, University of Colorado Anschutz, University of California, San Francisco, UCSF Benioff Children's Hospital

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,390