Impaired microvascular insulin-dependent dilation in women with a history of gestational diabetes
Year: 2024
Type: article
Study design: Observational Study
Abstract: Women who have gestational diabetes during pregnancy are at a greater risk for cardiovascular disease and type 2 diabetes in the decade following pregnancy. The mechanisms mediating this increased risk are unclear. Herein, we demonstrate that insulin-dependent microvascular responses are reduced in women who had gestational diabetes, despite the remission of glucose intolerance. This reduced microvascular sensitivity to insulin may contribute to increased cardiovascular disease and type 2 diabetes risk in these women.
Authors: Kelsey S. Schwartz, Paola V. Hernandez, Grace S. Maurer, Elizabeth M. Wetzel, Mingyao Sun, Diana I. Jalal, Anna E. Stanhewicz
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4401022751