Work

Evaluation of responses to both oral and parenteral immunization modalities for porcine epidemic diarrhea virus in production

Year: 2016

Type: article

Abstract: The immune responses (serum anti-porcine epidemic diarrhea virus [PEDV] immunoglobulin G [IgG] and milk antiviral neutralizing antibodies) induced by various combinations of two PEDV immunization modalities (vaccine and oral immunization) were examined in unrelated swine production units in different locations. Anti-PEDV antibodies were undetectable in serum and milk of the control group (non-vaccinated and non-infected). Sows in the unit that received only the PED vaccine (iPED+; Harrisvaccines, Inc, Ames, Iowa) (two doses) remained naive for the wild-type virus and did not develop milk anti-PEDV neutralizing immunoglobulin titers as high as those in the other three production units, which had received oral immunization. Milk anti-PEDV antibody titers in the orally immunized sows appeared to be of longer duration than serum antiviral IgG concentrations. This indicates that oral immunization may be the more efficacious PEDV immunization modality, especially with regard to the production of milk antiviral antibody levels.

Source: Journal of Swine Health and Production

DOI: 10.54846/jshap/896

Authors: Gail Scherba, Corinne Bromfield, Vickie Jarrell, Clifford Shipley

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Animal Virus Infections Studies

Subfield: Animal Science and Zoology

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: bronze

Funders: University of Illinois at Urbana-Champaign, National Institute of Food and Agriculture