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Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19

Year: 2024

Type: article

Abstract: This is a rare case report of a sudden shift to myopic astigmatism and topography alterations in a patient who experienced mild coronavirus disease 2019 (COVID-19) symptoms. A complete ophthalmologic evaluation, slit-lamp examination, corneal topography, and tear sampling for biochemical analysis were performed. Elevated corneal K-values were found, indicating abnormal anterior corneal curvature, based on the asymmetric corneal steepening index (cone location and magnitude index) in a Galilei G6 study. Tear analysis demonstrated elevated levels of interleukin (IL)-1β, IL-6, IP-10, IL-8, interferon-β, and prometalloproteinase-9. Ophthalmologists should maintain a high level of suspicion when symptoms suggestive of corneal involvement arise in patients recently infected with severe acute respiratory syndrome coronavirus 2.

Source: Indian Journal of Ophthalmology - Case Reports

DOI: 10.4103/ijo.ijo_221_24

Authors: Víctor Reviglio, Laura Almada, María Constanza Paz, María Cecilia Sanchez, Matías Osaba, Eva V Acosta Rodriguez, Ingrid Strusberg

Institutions: Universidad Católica de Córdoba, Fundacion Allende, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Córdoba

Language: English

Topic: Retinal and Optic Conditions

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4401135223

FWCI:

Cites: 16

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Related to: 10