Work

Automated radiosynthesis and preclinical imaging of a novel [ 18 F]fluorolidocaine analogue via sequential C–H radiolabelling

Year: 2024

Type: article

Abstract: 1.5 inhibitor, and compare this agent to a previously described analogue. Evidence from rodent and non-human primate PET imaging experiments suggests that the imaging utility of these agents may be limited by rapid metabolism and clearance.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d4md00293h

Authors: Madison Frazier, Jay S. Wright, David M. Raffel, Jenelle Stauff, Wade P. Winton, Peter J. H. Scott, Allen F. Brooks

Institution: University of Michigan

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Awards: G4689635561, G6262413698, G9000017831

OpenAlex ID: W4401167747

FWCI:

Cites: 16

Cited by:

Related to: 10