Contemporary Surgical Treatment for Management of Cholangiocarcinoma
Year: 2024
Type: book-chapter
Abstract: Cholangiocarcinoma is the second most common cause of liver cancer and is often in advanced stages at the time of diagnosis. The disease is classified and treated by anatomic location - distal, perihilar, and intrahepatic. Diagnosis and staging workup consists of laboratory analysis including liver function, bilirubin, and tumor markers, as well as cross sectional imaging and endoscopic evaluation. Early multidisciplinary management between Hepatology, Oncology, and Surgery teams is necessary to optimize outcomes. Currently, only patients with perihilar cholangiocarcinoma are eligible for wait-list prioritization at liver transplant based on the Mayo Clinic criteria. New evidence may support the extension of eligibility for liver transplant to intrahepatic cholangiocarcinoma. As such, expanded transplant exception criteria have been proposed. Continued advances in medical and radiation therapy along with liver transplant promise to increase the treatment options and survival from patients with cholangiocarcinoma.
Source: IntechOpen eBooks
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4401220133