Work

Figure S6 from DROSHA Regulates Mesenchymal Gene Expression in Wilms Tumor

Year: 2024

Type: other

Abstract: Supplementary Figure S6. Metabolomics of Wilms tumors were used to determine differential abundance of metabolites, expressed as log2-fold-change in tumors with microRNA processing mutations versus without such mutations, demonstrating that the antioxidant BH4 is depleted in tumors with microRNA processing mutations.

DOI: 10.1158/1541-7786.26467015.v1

Authors: Patricia D.B. Tiburcio, Kavita Desai, Jiwoong Kim, Qinbo Zhou, Lei Guo, Xue Xiao, Li Zhou, Aysen Yuksel, Daniel R. Catchpoole, James F. Amatruda, Lin Xu, Kenneth S. Chen

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4401273928

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