Work

EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth

Year: 2024

Type: article

Source: Oncogene

DOI: 10.1038/s41388-024-03119-9

Authors: Joshua Corbin, Xufen Yu, Jian Jin, Ling Cai, Gang Greg Wang

Institutions: Duke University, Duke Cancer Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, University of North Carolina at Chapel Hill, Duke Medical Center

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute

Awards: G1130814538, G1940748766, G2297578197, (PQ9) Developing EZH2 Degraders for Treating Triple-Negative Breast Cancer, G4771363279, The Role of YY1 in Castration-Resistant Prostate Cancer, G770722518, G773901830, G8436689808, Dissecting and targeting canonical and non-canonical oncogenic functions of EZH2 in caner, Cancer Center Support Grant

OpenAlex ID: W4401386353

FWCI: 2.205

Cites: 58

Cited by: 19

Related to: 10