Get started
Work

Autocatalytic, Brain Tumor‐Targeting Delivery of Bardoxolone Methyl Self‐Assembled Nanoparticles for Glioblastoma Treatment

Year: 2024
Type: article
Abstract: Glioblastoma Treatment In article number 2400081, Qianxue Chen, Xuan Xiao, Shenqi Zhang, and co-workers developed and validated a novel nanotechnology-based approach for glioblastoma treatment. They synthesized autocatalytic, brain tumor-targeting nanoparticles composed of self-assembled bardoxolone methyl. The resulting p28-LBM nanoparticles demonstrate remarkable capability in penetrating brain tumors and exhibit high efficacy in inhibiting glioblastoma growth. This approach represents a promising new avenue for improving outcomes in patients with glioblastoma.
DOI: 10.1002/smsc.202470027
Authors: Zhang Ye, Wendy C. Sheu, Huan Qu, Bin Peng, Jia Liu, Li Zhang, Fanen Yuan, Yuxin Wei, Jiangbing Zhou, Qianxue Chen, Xuan Xiao, Shenqi Zhang
Language: English
Subfield: Biomaterials
Open Access status: gold
Estimated APC paid: $5,770
OpenAlex ID: W4401429047
FWCI: 0.085
Cites:
Cited by: 1
Related to: 10