Work

Collision tumor comprised of chronic lymphocytic leukemia and myxopapillary ependymoma

Year: 2024

Type: article

Abstract: Background: Collision tumors involving the co-occurrence of two morphologically and genomically distinct neoplasms in the same anatomical site are exceptionally rare in the central nervous system (CNS). Case Description: We report a unique case of a CNS collision tumor comprising chronic lymphocytic leukemia and myxopapillary ependymoma in a 77-year-old male with acute neurological decline. Presumed to represent leukemic infiltration, urgent laminectomy was pursued for tissue diagnosis and spinal cord decompression, revealing the unexpected ependymal component. Conclusion: This case highlights the diagnostic and therapeutic challenges inherent to managing collision CNS tumors, particularly when one neoplasm is hematological.

Source: Surgical Neurology International

DOI: 10.25259/sni_658_2023

Authors: Ahmed Aly, Santhosh Nagaraju, Rupert Price

Institutions: University Hospitals of North Midlands NHS Trust, University Hospitals Birmingham NHS Foundation Trust

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4401464004

FWCI: 0.471

Cites: 10

Cited by: 2

Related to: 10