Work

Hypertension restricts leg blood flow and aggravates neuromuscular fatigue during human locomotion in males

Year: 2024

Type: article

Abstract: The impact of primary hypertension on the cardiovascular and neuromuscular fatigue response to locomotor exercise is unknown. We compared central and peripheral hemodynamics and the development of central and peripheral fatigue during cycling exercise in patients with stage I/II hypertension and age- and activity-matched healthy individuals. In addition to a significantly elevated blood pressure, hypertensive patients were, compared with their nonhypertensive counterparts, also characterized by considerable leg blood flow limitations and impaired neuromuscular fatigue resistance.

Source: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

DOI: 10.1152/ajpregu.00117.2024

Authors: Taylor S. Thurston, Joshua C. Weavil, Hsuan-Yu Wan, Mark A. Supiano, Philip A. Kithas, Markus Amann

Institutions: University of Utah, VA Salt Lake City Healthcare System, Lake City VA Medical Center

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, National Heart, Lung, and Blood Institute