Work

Precision epigenetic editing: Technological advances, enduring challenges, and therapeutic applications

Year: 2024

Type: review

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2024.07.007

Authors: Goldie V. Roth, Isabella R. Gengaro, Lei S. Qi

Institutions: Stanford University, Chan Zuckerberg Biohub San Francisco

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institute on Aging, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: Development of multi-color 3D super-localization LiveFISH and LiveFISH PAINT to investigate the chromatin dynamics at any genomic scale, Probing relationships between DNA methylation and cellular senescence with high-throughput CRISPR-based epigenetic editing, Manipulating and Interrogating Spatial Transcriptomics, High resolution dissection of oncogene enhancer networks via CRISPR screening and live-cell imaging., Graduate Training Program in Biotechnology

OpenAlex ID: W4401512124

FWCI: 2.124

Cites: 264

Cited by: 54

Related to: 10