Work

Modular 1,2‐Selective Carboarylation of Conjugated Dienes Under Cobalt Catalysis

Year: 2024

Type: article

Abstract: A highly 1,2‐regioselective cobalt‐catalyzed alkylarylation of conjugated dienes in a stereoretentive fashion has been disclosed. Indeed, the anion‐coordination played a critical role for tuning the reactivity of arylzinc pivalates, thereby efficiently steering the cobalt‐catalyzed three‐component coupling reaction via radical relay pathway. Moreover, this protocol also distinguished by its mild conditions, ample substrate scope and good functional group compatibility.

Source: ChemCatChem

DOI: 10.1002/cctc.202401063

Authors: Kaixin Chen, Jie Lin, Jiawei Guo, Haihong Chen, Jie Li

Institution: Soochow University

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province

Awards: G6454734509, G689882034, G8665970092