Work

Escherichia coli persisters in biofilm can perform horizontal gene transfer by transformation

Year: 2024

Type: article

Abstract: per cell) from dead cells to surviving persisters within the biofilms. Plasmid transfer was DNase-sensitive and also occurred by adding purified plasmid DNA to plasmid-free biofilms, demonstrating a transformation mechanism. This marks the first evidence of persisters' novel ability for horizontal gene transfer, via transformation.

Source: Biochemical and Biophysical Research Communications

DOI: 10.1016/j.bbrc.2024.150549

Authors: Tsubasa Nasu, Sumio Maeda

Institution: Nara Women's University

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,880

Funders: Institute for Fermentation, Osaka, Japan Society for the Promotion of Science