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Discovery of novel 2-substituted 2, 3-dihydroquinazolin-4(1H)-one derivatives as tubulin polymerization inhibitors for anticancer therapy: The in vitro and in vivo biological evaluation

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Year: 2024
Type: article
Source: European Journal of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2024.116766
Authors: Cai Shi, Boning Yang, Zhaolong He, Jingxiang Yang, Ling Li, Jian Song, Shiqiang Xu, Wei Song, Jian Yang
Institutions: Renmin Hospital of Wuhan University, The University of Sydney, Wuhan University of Science and Technology, Wuhan Children's Hospital, Huazhong University of Science and Technology
Language: English

Topic: Synthesis and biological activity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: green

Funder: National Natural Science Foundation of China
Awards: 棉酚和金刚烷酸两类新衍生物抗禽流感病毒活性及其机制, 基于水溶性棉酚衍生物骨架的新型HIV-1gp41膜融合抑制剂研究
OpenAlex ID: W4401531419
FWCI: 1.944
Cites: 25
Cited by: 14
Related to: 10
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