Work

Let’s get biophysical – How to get your favorite protein’s digits

Year: 2024

Type: review

Abstract: In these days of information overload and high-throughput analysis, it is easy to lose focus on the study of individual proteins. It is our conjecture that such investigations are still crucially important and offer uniquely penetrative insights. We thus present a discussion of biophysical methods to allow readers to get to know their protein of interest better. Although this perspective is not written with the expert in mind, we hope that for interdisciplinary scientists, or researchers who do not routinely perform biophysical analyses, the content will be helpful and inspiring.

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2024.117873

Authors: Marcus J.C. Long, Yimon Aye

Institutions: University of Lausanne, École Polytechnique Fédérale de Lausanne

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,840

Funders: Novartis Foundation, École Polytechnique Fédérale de Lausanne, Novartis Stiftung für Medizinisch-Biologische Forschung