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Clinical Benefits of Octreotide for Managing Persistent Gastrointestinal Fluid Loss in Malignant Small Bowel Obstruction: A Case Report and Literature Review

Year: 2024
Type: article
Study design: Case Report
Abstract: Malignant small bowel obstruction (mSBO) is a frequent complication in patients with gastrointestinal or gynecologic cancers. For those with inoperable cancers and persistent obstructive symptoms, symptom palliation with a percutaneous gastrostomy tube (PGT) may be required. However, excessive fluid loss from the PGT can lead to significant fluid, electrolyte, and acid-base imbalances. We present a case of a man with metastatic colonic adenocarcinoma who developed mSBO, acute kidney injury, and metabolic alkalosis, all of which were effectively managed with octreotide.
Source: Cureus
DOI: 10.7759/cureus.66785
Authors: Chalothorn Wannaphut, Landon A Kozai, Narathorn Kulthamrongsri, Chutawat Kookanok, Wanprapit Noree, Kamonluk Rodsom, Ekamol Tantisattamo, Jared Acoba
Institutions: University of Hawaiʻi at Mānoa, American Heart Association, University of Hawaii System, Siriraj Hospital, University of California, Irvine, Mahidol University, University of California, Irvine Medical Center, Queen's Medical Center, Phramongkutklao College of Medicine
Language: English
Field: Nursing
Open Access status: diamond
OpenAlex ID: W4401538399
FWCI:
Cites: 15
Cited by:
Related to: 10