Year: 2024
Type: article
Abstract: Introduction: The chronic use of diazepine medication is increasing and, in addition, without a prescription or adequate medical prescription.It leads to changes in the GABA receptor, reducing its affinity for its neurotransmitter and decreasing GABAergic activity.This is manifested in the form of tolerance to the drug (MOSFIAK, 2020).Objective: To review the risks related to diazepine dependence and management of its withdrawal.Result: Unfortunately, there is still no robust evidence that any medication can be used to aid withdrawal from diazepines after prolonged use, although some research and reviews have been carried out in this regard (MOSFIAK, 2020).Conclusion: The chronic use of diazepine medication is increasing and, in addition, without a prescription or adequate medical prescription.It leads to changes in the GABA receptor, reducing its affinity for its neurotransmitter and decreasing GABAergic activity.This is manifested in the form of tolerance to the drug (MOSFIAK, 2020).
Authors: Elma Oliveira Alves Monteiro, Aline Galdino Goiz, Layo Abreu Machado, Samanttha Cristina da Silva Chaves, Anny Izumi Toma, Flávio Henrique Alves, Sarah Frota Loiola, Mainara de Queiroz Moreira, Alciléa Barbosa de Andrade Vila Flor, Ayumi Fukuyama Parra, Laura Oliveira Lorenzo de Andrade, Luiz Gustavo De Sant’Anna Santos, Paulo Henrique Faria Domingues
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4401592747