Work

The complexity of cerebral blood flow regulation: the interaction of posture and vasomotor reactivity

Year: 2024

Type: article

Abstract: Data from supine, sitting, and standing postures were measured. Modeling the data with logistic curves to express the effects of CO2 reactivity on middle cerebral artery blood velocity (MCAv), posterior cerebral artery blood velocity (PCAv), heart rate, blood pressure (BP), and the autoregulation index (ARI), provided a more comprehensive approach to study the interaction of arterial CO2 with posture than in previous studies. Above all, shifts of the logistic curve model with changes in posture have shown interactions with [Formula: see text] that have not been previously demonstrated.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00851.2023

Authors: Rebecca H. Clough, Ronney B. Panerai, Kannaphob Ladthavorlaphatt, Thompson G. Robinson, Jatinder S. Minhas