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The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS

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Year: 2024
Type: article
Source: Angewandte Chemie
DOI: 10.1002/ange.202415168
Authors: Zhijie Deng, Li Chen, Chao Qian, Jing Liu, Qiong Wu, Xiangyang Song, Yan Xiong, Zhen Wang, Xiaoping Hu, Hiroyuki Inuzuka, Yue Zhong, Yufei Xiang, Yindan Lin, Ngoc Dung Pham, Yi Shi, Wenyi Wei, Jian Jin
Institutions: Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, Beth Israel Deaconess Medical Center, Harvard University, First Affiliated Hospital of Xi'an Jiaotong University
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Foundation for the National Institutes of Health
Awards: G1546909819, G3538542740, G5376580763, G5596622412
OpenAlex ID: W4401634236
FWCI: 0.118
Cites: 33
Cited by: 1
Related to: 10
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